Working Hypotheses & Rationale:
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Research Proposal
Speech understanding
Inferior colliculus lesions
Brainstem aphasia?

fMRI of the inferior colliculi
Testing strategies
Anticipated results

Working hypotheses
Language areas on fMRI
Effects of asphyxia at birth
Maturation of the brain
Time-table of myelination
Learning to speak "by ear"
Metabolism in the brain
Protective mechanisms
Catastrophic factors
Brainstem damage
Recent fMRI investigations of language disorder
in autism implicate “underconnectivity” and
differences from normal in brain symmetry [87-89]
Brain activation of autistic (A) and control (B) groups    
(Sentence versus Fixation contrast)
Autistic participants show less activation in the left
inferior frontal gyrus (LIFG) than the control group, but
more activation in the left posterior superior temporal
gyrus (LSTG) than the control group.
From Just MA et al. Brain. 2004 Aug;127(Pt 8):1811-21.
Differences from normal are evident
in the language areas of the cortex!
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But what impairs development
of the cortical language areas?
Refs >>
October 2006
Working version