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Research Proposal
Speech understanding
Inferior colliculus lesions
Brainstem aphasia?

fMRI of the inferior colliculi
Testing strategies
Anticipated results

Working hypotheses
Language areas on fMRI
Effects of asphyxia at birth
Maturation of the brain
Time-table of myelination
Learning to speak "by ear"
Metabolism in the brain
Protective mechanisms
Catastrophic factors
Brainstem damage
Monkeys subjected to asphyxia at birth displayed
transient delay in development of motor control.
Monkey with
developmental delay
They did eventually appear to “catch up.”
But examination of the brain many months or years later revealed
that brain growth had not progressed normally [90].
Neurons were sparser in: The oculomotor nuclei, reticular
formation, mammillary bodies, hippocampus, amygdala,
corpus callosum, cerebellum (Purkinje cells) and cerebral
cortex (parietal and frontal) than in normal monkeys.
These sites correspond to where changes are found
in the brains of people with life-long autism [91-92].
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October 2006
Working version