The possible importance of the inferior colliculi
for language development is based on four
major considerations:
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Research Proposal
Motivation
Speech understanding
Inferior colliculus lesions
Brainstem aphasia?

Plan
fMRI of the inferior colliculi
Subjects
Testing strategies
Anticipated results

Working hypotheses
Language areas on fMRI
Effects of asphyxia at birth
Maturation of the brain
Time-table of myelination
Learning to speak "by ear"
Metabolism in the brain
Protective mechanisms
Catastrophic factors
Brainstem damage
Maturation of the cerebral cortex continues after birth guided by
trophic neurotransmitters produced in neurons of brainstem nuclei
[96-98].
1.
The brainstem
auditory pathway
is fully myelinated
and functional in
the human fetus
by 29 gestational
weeks [97, 98].
2.
Myelin in the
human brainstem
auditory pathway
at 25 gestational
weeks (sagittal
view).
Myelin in the
human brainstem
auditory pathway
at 29 gestational
weeks (horizontal
view).
Larger images >>>
Myelination of the later maturing target areas for the
brainstem auditory pathway (the temporal and frontal
language areas of the cortex) continues over the first four
years of post-natal life.
3.
Thus children normally learn to speak “by ear” before the
language areas of the cortex are fully developed.
4.
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October 2006
Working version