The Biochemistry of Respiration
Auditory Agnosia
Learning to Speak
Personal Interest
The Bohr Effect
Blood flow in the brain
Vigilance center
Aerobic metabolism
Metabolism in the brain
Cardiac arrest
Asphyxia/ suffocation

Alcohol toxicity
Pyrithiamine poison
Thiamine deficiency

Other poisons
Auditory agnosia
Time-table of myelination
Trophic growth factors
During an hypoxic episode hemoglobin provides
immediate adjustment that protects tissues of highest
metabolic rate, as described in one textbook:
“Primitive organisms rely on
diffusion through their
environmental media to provide
the oxygen needed for their
metabolism and to remove the
carbon dioxide produced.
Through the action of hemoglobin,
oxygen is abstracted from the air,
carried within a few seconds to
the most distant parts of the body,
and delivered to the tissues at a
pressure only slightly less than
that which it existed in the
The active metabolism of
mammalian tissues remote from
the atmosphere is possible
because of a mechanism which
provides constant delivery of
oxygen and removal of carbon
dioxide.  The magnitude of this
task may be appreciated from the
fact that a man oxidizing 3000 Cal.
Of mixed food per day uses about
600 liters of oxygen (27 moles)
and produces about 480 liters of
carbon dioxide (22 moles).
The CO2 produced daily by the
tissues becomes H2CO3, an acid,
in an amount equivalent to 2 liters
of concentrated hydrochloric acid;
yet all this acid normally pours
from the tissues, through the
blood, and out of the lungs with a
change in the pH of blood of no
more than few hundredths of a pH
White A, Handler P, Smith EL (1968) Principles of
Biochemistry, fourth edition. New York: McGraw-Hill.  
P 758 –  Chapter 32.  Chemistry of Respiration
December 2005                                                                                                                                                                              <<<<  8 >>>>